| Primary Identifier | MGI:109406 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 19695 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables hormone activity; oligosaccharide binding activity; and peptidoglycan binding activity. Involved in several processes, including negative regulation of keratinocyte differentiation; regulation of response to wounding; and response to bacterium. Acts upstream of or within response to bacterium. Located in secretory granule. Colocalizes with extracellular space. Is expressed in several structures, including epithelium; gut; pharyngo-tympanic tube; thymus; and trachea. Orthologous to human REG3G (regenerating family member 3 gamma). PHENOTYPE: Mice homozygous for a knock-out allele eshibit increased mucosal bacterial loads, T-helper 1 cells, and intestinal permeability. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
