| Primary Identifier | MGI:98475 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 21336 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable substance P receptor activity. Involved in regulation of uterine smooth muscle contraction. Acts upstream of or within response to pain. Located in cell periphery. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study attention deficit hyperactivity disorder. Human ortholog(s) of this gene implicated in developmental disorder of mental health and exercise-induced bronchoconstriction. Orthologous to human TACR1 (tachykinin receptor 1). PHENOTYPE: Homozygotes for targeted null mutations exhibit reduced anxiety, pain and stress-related responses, reduced immunological response after a viral challenge, and reduced inflammatory responses. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
