| Primary Identifier | MGI:1337004 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 16950 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables fibronectin binding activity and protein-lysine 6-oxidase activity. Involved in several processes, including fibronectin fibril organization; negative regulation of T-helper 17 cell lineage commitment; and peptidyl-lysine oxidation. Located in extracellular space. Is expressed in several structures, including alimentary system; connective tissue; limb mesenchyme; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in myopia. Orthologous to human LOXL3 (lysyl oxidase like 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality shortly after birth, craniofacial and vertebral abnormalities associated with collagen deformities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
