| Primary Identifier | MGI:1917087 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 69837 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable promoter-specific chromatin binding activity. Predicted to be involved in chromatin remodeling and negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of PcG protein complex. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; nervous system; and striated muscle tissue. Orthologous to human PCGF1 (polycomb group ring finger 1). PHENOTYPE: Mice homozygous for a null allele display embryonic lethality with impaired heart looping, abnormal embryo turning and abnormal neural tube closure. Mice with loss of expression in the enteric nervous system show reduced postnatal growth and survival. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
