Primary Identifier | MGI:2443220 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 232156 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sodium:bicarbonate symporter activity. Acts upstream of or within several processes, including cerebrospinal fluid secretion; mitochondrion distribution; and retina development in camera-type eye. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including nervous system; retina; and thyroid gland. Orthologous to human SLC4A5 (solute carrier family 4 member 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit arterial hypertension and renal metabolic acidosis. [provided by MGI curators] |