Primary Identifier | MGI:1859834 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 51811 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables galactose binding activity and glycolipid binding activity. Acts upstream of or within NK T cell activation. Located in plasma membrane. Is expressed in liver; liver lobe; and liver sinusoid. Orthologous to human CLEC4F (C-type lectin domain family 4 member F). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired IFN-gamma secretion from Kupffer cells stimulated with alpha-GalCer. [provided by MGI curators] |