| Primary Identifier | MGI:1261912 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 330369 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Acts upstream of or within several processes, including chemical synaptic transmission; nervous system development; and walking behavior. Is active in centrosome and cytoplasm. Is expressed in several structures, including forelimb bud; male reproductive gland or organ; nervous system; notochord; and sensory organ. Orthologous to human FBXO41 (F-box protein 41). PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal lethality and premature death by 10 weeks, growth retardation, abnormal gait, dragging hindlimbs, ataxia, impaired balance, impaired coordination, tremors and abnormal neuronal migration. [provided by MGI curators] |