| Primary Identifier | MGI:1919352 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 72102 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity; polynucleotide 5'-phosphatase activity; and protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in fibrillar center; intercellular bridge; and nuclear speck. Is expressed in central nervous system and retina. Orthologous to human DUSP11 (dual specificity phosphatase 11). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased mortality and cytokine production in response to LPS-induced endotoxic shock. Bone marrow-derived macrophages show enhanced LPS-induced macrophage activation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
