| Primary Identifier | MGI:1349421 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 26910 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Is expressed in follicle cell of primary follicle; oocyte of primary follicle; oocyte of secondary follicle; and ovary. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 6. Orthologous to human FIGLA (folliculogenesis specific bHLH transcription factor). PHENOTYPE: Inactivation of this locus results in female sterility owing to an absence of primordial follicles and oocyte depletion. Mutant males are fertile and exhibit no apparent defects of the reproductive system. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
