Primary Identifier | MGI:1345635 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 23983 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific single stranded DNA binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is active in cytosol. Is expressed in embryo. Orthologous to human PCBP1 (poly(rC) binding protein 1). PHENOTYPE: Mice heterozygous for a knock-out allele exhibit reduced body weight. Mice homozygous for the allele exhibit embryonic lethality between E3.5 and E8.5. [provided by MGI curators] |