| Primary Identifier | MGI:88431 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 12785 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable nucleic acid binding activity and translation regulator activity. Involved in positive regulation of DNA-templated transcription. Acts upstream of or within positive regulation of cell population proliferation and positive regulation of transcription by RNA polymerase II. Located in cytosol; endoplasmic reticulum; and nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; egg cylinder; and genitourinary system. Human ortholog(s) of this gene implicated in myotonic dystrophy type 2. Orthologous to human CNBP (CCHC-type zinc finger nucleic acid binding protein). PHENOTYPE: Mice homozygous for a retroviral insertion die around E10.5 showing abnormal anterior visceral endoderm formation, reduced embryonic neuroepithelial cell proliferation, lack of anterior definitive endoderm and anterior neuroectoderm, absent diencephalon and telencephalon, and forebrain truncation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
