Primary Identifier | MGI:1340024 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 107747 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables formyltetrahydrofolate dehydrogenase activity. Involved in 10-formyltetrahydrofolate catabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; brown fat; genitourinary system; nervous system; and sensory organ. Orthologous to human ALDH1L1 (aldehyde dehydrogenase 1 family member L1). PHENOTYPE: Mice homozygous for a null allele exhibit folate deficiency and impaired glycine metabolism with a decrease in glycine and glycine conjugates in the liver. [provided by MGI curators] |