| Primary Identifier | MGI:2385252 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 232232 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable histone deacetylase activity. Predicted to be involved in epigenetic regulation of gene expression and oligodendrocyte development. Predicted to be located in nucleus and plasma membrane. Predicted to be part of histone deacetylase complex. Is expressed in brain; cerebral cortex ventricular layer; cortical plate; and retina. Orthologous to human HDAC11 (histone deacetylase 11). PHENOTYPE: Mice homozygous for a knockout allele exhibit increased IL10 secretion from peritoneal elicited macrophages stimulated with LPS, more suppressive myeloid-derived suppressive cell population and enhanced tumor growth of injected tumor cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
