| Primary Identifier | MGI:98823 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 22044 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable thyrotropin-releasing hormone activity. Acts upstream of or within adult walking behavior. Predicted to be located in extracellular region. Predicted to be active in secretory granule. Is expressed in several structures, including central nervous system; embryo endoderm; gut; neural ectoderm; and renal vasculature. Orthologous to human TRH (thyrotropin releasing hormone). PHENOTYPE: Homozygotes for targeted null mutations exhibit high postnatal mortality, impaired thermoregulation, and loss of white fat. Survivors show ketosis, microvesicular fat accumulation, elevated serum lipids, and behavioral abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
