Primary Identifier | MGI:1916320 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 101401 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables endopeptidase activity. Involved in several processes, including circulatory system development; negative regulation of endothelial cell migration; and negative regulation of sprouting angiogenesis. Acts upstream of or within several processes, including camera-type eye development; positive regulation of melanocyte differentiation; and response to bacterium. Located in cell surface and extracellular space. Is expressed in several structures, including alimentary system; embryo mesenchyme; endocrine gland; eye; and genitourinary system. Orthologous to human ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9). PHENOTYPE: Homozygous null mice display embryonic lethality before somite formation. Mice heterozygous for a knock-out or ENU-induced allele exhibit a ring of epidermal hypopigmentation in the tail. [provided by MGI curators] |