Primary Identifier | MGI:1306824 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 20917 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GDP binding activity; succinate-CoA ligase (GDP-forming) activity; and succinate-semialdehyde dehydrogenase (NAD+) activity. Predicted to be involved in succinate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Located in mitochondrion. Part of succinate-CoA ligase complex (GDP-forming). Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SUCLG2 (succinate-CoA ligase GDP-forming subunit beta). PHENOTYPE: Homozygous knockout with a gene trap is embryonic lethal. Heterozygosity has a mild effect on mitochondrial respiration. [provided by MGI curators] |