Primary Identifier | MGI:1202299 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 14761 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Acts upstream of or within positive regulation of insulin secretion involved in cellular response to glucose stimulus and positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway. Located in plasma membrane. Orthologous to human GPR27 (G protein-coupled receptor 27). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased body weight, mildly impaired glucose tolerance, and decreased plasma insulin levels but normal insulin tolerance. [provided by MGI curators] |