| Primary Identifier | MGI:1929059 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 56353 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity and transcription corepressor activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. Is expressed in several structures, including central nervous system; early embryo; extraembryonic component; genitourinary system; and hemolymphoid system gland. Orthologous to human RYBP (RING1 and YY1 binding protein). PHENOTYPE: Homozygous null mice initiate implantation but fail to complete decidualization and display early embryonic lethality. A subset of heterozygotes show forebrain overgrowth, delayed neural tube closure, exencephaly, failed optic fissure closure, malformed lenses, and retinal/optic nerve colobomas. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
