Primary Identifier | MGI:1098266 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 12661 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protease binding activity. Involved in negative regulation of neuron apoptotic process. Acts upstream of or within several processes, including adult locomotory behavior; exploration behavior; and generation of neurons. Located in apical part of cell and dendrite. Is expressed in head mesenchyme; nervous system; and retina. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CHL1 (cell adhesion molecule L1 like). PHENOTYPE: Homozygous mutation of this gene results in enlargement of the lateral ventricles and altered hippocampal mossy fiber organization. Mutant animals exhibit altered exploratory behavior. [provided by MGI curators] |