Primary Identifier | MGI:106038 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 16979 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within positive regulation of synapse assembly. Predicted to be located in membrane. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including central nervous system; dorsal root ganglion; embryo mesenchyme; lip; and sensory organ. Orthologous to human LRRN1 (leucine rich repeat neuronal 1). PHENOTYPE: Mice homozygous for one null allele exhibit decreased exploratory activity and females exhibit increased anxiety-like response during open field testing. Mice homozygous other null alleles display abnormal cochlear inner hair cells. [provided by MGI curators] |