Primary Identifier | MGI:1914416 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 67166 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein activity; guanyl ribonucleotide binding activity; and tubulin binding activity. Involved in several processes, including antigen processing and presentation of polysaccharide antigen via MHC class II; late endosome to lysosome transport; and viral exocytosis. Acts upstream of or within endosomal transport. Located in axon; lysosome; and synapse. Is expressed in several structures, including alimentary system; brain; extraembryonic component; limb; and sensory organ. Orthologous to human ARL8B (ARF like GTPase 8B). PHENOTYPE: Mice homozygous for a null mutation display perinatal lethality with impaired visceral yolk sac function and reduced embryo size. [provided by MGI curators] |