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Protein Coding Gene : Edem1 ER degradation enhancer, mannosidase alpha-like 1
Primary Identifier  MGI:2180139 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  192193
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Involved in positive regulation of retrograde protein transport, ER to cytosol and trimming of terminal mannose on C branch. Acts upstream of or within ERAD pathway. Located in endoplasmic reticulum membrane. Is expressed in embryo and liver. Orthologous to human EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1).
  • synonyms:
  • mKIAA0212,
  • Edem1,
  • MGI:2442942,
  • ER degradation enhancer, mannosidase alpha-like 1,
  • RIKEN cDNA A130059K23 gene,
  • A130059K23Rik
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1 Involved In Mutations

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