Primary Identifier | MGI:1915724 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 101206 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables nuclear receptor coactivator activity. Involved in regulation of cell cycle; regulation of cell division; and regulation of embryonic development. Acts upstream of or within several processes, including chromatin organization; regulation of protein modification process; and regulation of protein stability. Located in mitotic spindle and nucleus. Part of ATAC complex and SAGA complex. Is expressed in eye; ureteric tip; and ureteric trunk. Orthologous to human TADA3 (transcriptional adaptor 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality between E3.5 and E8.5 associated with impaired proliferation of trophoblast cells and absence of inner cell mass. [provided by MGI curators] |