Primary Identifier | MGI:1889371 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 57890 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable interleukin-17 receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and inflammatory response. Predicted to be located in cytoplasm; extracellular region; and plasma membrane. Is expressed in urinary system. Orthologous to human IL17RE (interleukin 17 receptor E). PHENOTYPE: Homozygous mice exhibit increased susceptibility to DSS-induced colitis, imiquimod-induced psoriasis, and C. rodentium bacterial infection. [provided by MGI curators] |