| Primary Identifier | MGI:2159336 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 171095 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables signaling receptor binding activity. Involved in defense response to fungus; granulocyte chemotaxis; and positive regulation of interleukin-6 production. Acts upstream of or within positive regulation of cytokine production involved in inflammatory response. Located in cell surface and plasma membrane. Is expressed in hip; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in chronic mucocutaneous candidiasis. Orthologous to human IL17RC (interleukin 17 receptor C). PHENOTYPE: Mice homozygous for a reporter allele exhibit increased interleukin-17 secretion, reduced chemokine expression, and decreased susceptibility to experimental autoimmune encephalomyelitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
