| Primary Identifier | MGI:1915406 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 101314 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Predicted to contribute to small GTPase binding activity. Acts upstream of or within several processes, including actin cytoskeleton organization; in utero embryonic development; and positive regulation of fibroblast proliferation. Located in lamellipodium. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; lung; and nervous system. Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex). PHENOTYPE: Mice homozygous for disruptions in this gene display partial embryonic lethality before implantation with abnormalities in the actin network and failure of cultured embryos to hatch from the zona pellucida. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
