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Protein Coding Gene : Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11
Primary Identifier  MGI:95630 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  243616
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables gamma-aminobutyric acid:sodium:chloride symporter activity and taurine:sodium symporter activity. Involved in neurotransmitter uptake. Is active in synapse. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and liver and biliary system. Orthologous to human SLC6A11 (solute carrier family 6 member 11).
PHENOTYPE: Mice homozygous for a targeted mutation display postnatal lethality. Mice heterozygous for a targeted mutation display resistance to pharmacologically induced seizures. [provided by MGI curators]
  • synonyms:
  • MGI:1925977,
  • MGI:2443874,
  • RIKEN cDNA E130202I16 gene,
  • E130202I16Rik,
  • D930045G19Rik,
  • Gat3,
  • Gabt4,
  • Slc6a11,
  • gamma-aminobutyric acid (GABA-A) transporter 4,
  • GAT4,
  • RIKEN cDNA D930045G19 gene,
  • MGD-MRK-9950,
  • solute carrier family 6 (neurotransmitter transporter, GABA), member 11
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Features --> Cross References

Genome

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0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

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Mouse features --> Functions (GO terms)

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Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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2 Driver For





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