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Protein Coding Gene : Vgll4 vestigial like family member 4

Primary Identifier  MGI:2652840 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  232334
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable transcription coactivator binding activity. Involved in negative regulation of cardiac muscle cell proliferation; negative regulation of hippo signaling; and regulation of primary metabolic process. Located in nucleus. Is expressed in lung; submandibular gland primordium; tooth; and vibrissa. Orthologous to human VGLL4 (vestigial like family member 4).
PHENOTYPE: Mice homozygous for a null allele exhibit premature death associated with compensatory cardiac hypertrophy, increased cardiac contractility, and thickening of the aortic and pulmonary valves due to increased cellular proliferation. [provided by MGI curators]
  • synonyms:
  • vestigial like family member 4,
  • MGC:54805,
  • VGL-4,
  • BC048841,
  • Vgll4,
  • cDNA sequence BC048841

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For