| Primary Identifier | MGI:1914277 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 67027 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ubiquitin protein ligase activity. Involved in negative regulation of inflammatory response to antigenic stimulus; negative regulation of non-canonical NF-kappaB signal transduction; and ubiquitin-dependent protein catabolic process. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. Orthologous to human MKRN2 (makorin ring finger protein 2). PHENOTYPE: Homozygous male mice are infertile, with abnormal sperm characterized by low number, poor motility, and aberrant morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
