| Primary Identifier | MGI:1919029 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 71779 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables MHC class II protein binding activity and ubiquitin protein ligase activity. Involved in antigen processing and presentation of peptide antigen via MHC class II; negative regulation of MHC class II biosynthetic process; and protein ubiquitination. Predicted to be located in endosome. Predicted to be active in early endosome membrane; late endosome membrane; and lysosome. Orthologous to human MARCHF8 (membrane associated ring-CH-type finger 8). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a normal CD4+ T cell compartment in the thymus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
