Primary Identifier | MGI:98959 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 22419 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables signaling receptor binding activity. Acts upstream of or within negative regulation of canonical Wnt signaling pathway and positive regulation of fat cell differentiation. Located in cell surface and extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human WNT5B (Wnt family member 5B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal numbers of thoracic motor neurons and proportions of motor columnar subtypes. [provided by MGI curators] |