Primary Identifier | MGI:101949 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 19365 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and single-stranded DNA binding activity. Involved in DNA double-strand break processing involved in repair via single-strand annealing. Acts upstream of or within cellular response to oxidative stress and double-strand break repair via homologous recombination. Predicted to be part of protein-DNA complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung cancer (multiple); mucoepidermoid carcinoma; and nicotine dependence. Orthologous to human RAD52 (RAD52 homolog, DNA repair protein). PHENOTYPE: Mice homozygous for a null allele exhibit normal reproductive and immune systems. [provided by MGI curators] |