| Primary Identifier | MGI:1918885 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 328329 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cytoskeleton organization and intracellular signal transduction. Predicted to be located in cytoplasm. Predicted to be active in microtubule cytoskeleton. Is expressed in brain; thymus primordium; and ventral grey horn. Used to study Sertoli cell-only syndrome. Orthologous to human MAST4 (microtubule associated serine/threonine kinase family member 4). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit abnormal incisor development, abnormal enamel maturation, malocclusion, amelogenesis imperfecta, and male infertility with male germ cell depletion. [provided by MGI curators] |