Primary Identifier | MGI:1354387 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 50530 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable extracellular matrix constituent conferring elasticity. Involved in definitive hemopoiesis. Acts upstream of or within supramolecular fiber organization. Located in extracellular matrix. Is expressed in aorta; dentate gyrus subgranular zone; esophagus; genitourinary system; and skeletal musculature. Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Orthologous to human MFAP5 (microfibril associated protein 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased circulating neutrophils. [provided by MGI curators] |