Primary Identifier | MGI:95757 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 20527 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables D-glucose transmembrane transporter activity and dehydroascorbic acid transmembrane transporter activity. Involved in D-glucose transmembrane transport and dehydroascorbic acid transport. Located in acrosomal membrane and plasma membrane. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; early conceptus; and genitourinary system. Orthologous to several human genes including SLC2A3 (solute carrier family 2 member 3). PHENOTYPE: Homozygous null mutations cause embryonic lethality. Heterozygotes for a null allele show partial perinatal lethality and impaired placental transport. Heterozygotes for a gene trap allele show abnormal brain wave patterns, increased startle reflex, reduced prepulse inhibition and increased anxiety. [provided by MGI curators] |