| Primary Identifier | MGI:2685918 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 381810 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Acts upstream of or within behavioral response to pain and positive regulation of CREB transcription factor activity. Predicted to be located in plasma membrane. Is expressed in several structures, including future brain; genitourinary system; gut; immune system; and nervous system. Orthologous to human LPAR5 (lysophosphatidic acid receptor 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit resistance to neuropathic pain and myelin sheath alterations. Mice homozygous for a different targeted allele exhibit decreased nociception sensitivity, decreased anxiety-related response and enhanced coordination and spatial learning. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
