| Primary Identifier | MGI:95640 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 14433 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables enzyme binding activity and glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Involved in canonical glycolysis; gluconeogenesis; and negative regulation of translation. Located in cytoplasm and plasma membrane. Part of GAIT complex. Is active in cytosol. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). PHENOTYPE: Mutant heterozygotes show reduced enzyme levels. The currently known mutant allels are homozygous lethal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
