| Primary Identifier | MGI:1915548 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 68298 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable histone binding activity. Involved in positive regulation of chromosome segregation and positive regulation of chromosome separation. Located in condensed nuclear chromosome and pronucleus. Part of condensin complex. Is expressed in several structures, including central nervous system; retina outer nuclear layer; and salivary gland. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPD2 (non-SMC condensin I complex subunit D2). PHENOTYPE: Mice heterozygous for a null allele exhibit decreased susceptibility to AOM/DSS-induced colorectal cancer and colitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
