| Primary Identifier | MGI:1095406 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 22144 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within male germ-line stem cell population maintenance. Located in ciliary basal body and microtubule. Is expressed in several structures, including gonad; liver; lung; muscle tissue; and spleen. Human ortholog(s) of this gene implicated in keratoconus. Orthologous to several human genes including TUBA3C (tubulin alpha 3c) and TUBA3D (tubulin alpha 3d). PHENOTYPE: Mice homozygous for a null allele exhibit normal testis size and fertility. Mice homozygous for both Tuba3a and 3b exhibit small testis and postnatal depletion of germ cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
