Primary Identifier | MGI:2387214 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 243634 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and intracellularly calcium-gated chloride channel activity. Acts upstream of or within chloride transport and establishment of localization in cell. Located in neuron projection; non-motile cilium; and plasma membrane. Is active in glutamatergic synapse and presynaptic membrane. Is expressed in dorsal root ganglion; epidermis; medulla oblongata basal plate mantle layer; olfactory epithelium; and spinal cord mantle layer. Orthologous to human ANO2 (anoctamin 2). PHENOTYPE: Mice homozygous for a knock-out allele lack calcium-activated chloride currents in the main olfactory epithelium and vomeronasal organ but normal olfaction in behavioral tasks. [provided by MGI curators] |