| Primary Identifier | MGI:96654 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 16485 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables delayed rectifier potassium channel activity. Involved in several processes, including cellular response to magnesium ion; detection of mechanical stimulus involved in sensory perception; and nervous system development. Located in several cellular components, including axon; cell surface; and perikaryon. Part of voltage-gated potassium channel complex. Is active in axon initial segment. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; immune system; and nervous system. Used to study epilepsy; episodic ataxia type 1; and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in episodic ataxia type 1. Orthologous to human KCNA1 (potassium voltage-gated channel subfamily A member 1). PHENOTYPE: Various mutations at this allele have diverse affects including behavioral abnormalities, megencephaly, and in one case, embryonic lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
