| Primary Identifier | MGI:2141505 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 101187 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable NAD+-protein poly-ADP-ribosyltransferase activity. Acts upstream of or within nuclear envelope organization. Predicted to be located in cytosol; nuclear body; and nuclear envelope. Predicted to be part of nuclear pore. Predicted to be active in nucleus. Is expressed in several structures, including adrenal gland; alimentary system; nervous system; reproductive system; and thymus. Orthologous to human PARP11 (poly(ADP-ribose) polymerase family member 11). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired male fertility and teratozoospermia associated with sperm head malformations and nuclear envelope defects during the nuclear reshaping process of spermatid elongation and condensation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
