| Primary Identifier | MGI:106907 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 21679 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including embryo implantation; positive regulation of stem cell population maintenance; and trophectodermal cell fate commitment. Located in cytoplasm. Part of protein-DNA complex and transcription regulator complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; hemolymphoid system gland; and skeletal musculature. Orthologous to human TEAD4 (TEA domain transcription factor 4). PHENOTYPE: Mice homozygous for a null allele die prior to somitogenesis, lack trophoblast stem cells and develop abnormally. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
