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Protein Coding Gene : Clec2d C-type lectin domain family 2, member d

Primary Identifier  MGI:2135589 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  93694
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables natural killer cell lectin-like receptor binding activity. Acts upstream of or within negative regulation of osteoclast differentiation and protection from natural killer cell mediated cytotoxicity. Located in external side of plasma membrane. Is expressed in several structures, including gut; liver; skeleton; spleen; and urinary system. Orthologous to human CLEC2D (C-type lectin domain family 2 member D).
PHENOTYPE: Enhanced osteoclastic activity in the bone of homozygous null mice leads to osteopenia and high serum calcium levels. [provided by MGI curators]
  • synonyms:
  • C-type lectin domain family 2, member d,
  • Clr-b,
  • osteoclast inhibitory lectin,
  • Ocil,
  • Clec2d,
  • Clrb

Features --> Cross References

Genome

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0 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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