Primary Identifier | MGI:2444608 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 232414 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable carbohydrate binding activity. Involved in receptor-mediated endocytosis. Located in cell surface. Orthologous to human CLEC9A (C-type lectin domain containing 9A). PHENOTYPE: Homozygous null mice have CD8alpha+ dendritic cells that are defective in cross-presentation of dead-cell associated antigens. [provided by MGI curators] |