Primary Identifier | MGI:1261434 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 108078 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables low-density lipoprotein particle receptor activity. Predicted to be involved in leukocyte cell-cell adhesion; lipoprotein metabolic process; and negative regulation of gene expression. Predicted to be located in nucleoplasm. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; extraembryonic component; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in cerebral amyloid angiopathy; coronary artery disease; and myocardial infarction. Orthologous to human OLR1 (oxidized low density lipoprotein receptor 1). PHENOTYPE: Homozygous mutation of this gene results in no obvious phenotype. [provided by MGI curators] |