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Protein Coding Gene : Tas2r105 taste receptor, type 2, member 105

Primary Identifier  MGI:2681195 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  57252
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable bitter taste receptor activity. Acts upstream of or within sensory perception of bitter taste. Predicted to be active in membrane. Is expressed in tongue anterior part. Orthologous to human TAS2R10 (taste 2 receptor member 10).
PHENOTYPE: Mice homozygous for a null mutation respond normally to a variety of bitter, sweet, umami, salty and sour stimuli but show a striking and selective impairement in their ability to taste cycloheximide (a bitter tastant). In addition, homozygotes are no longer behaviorally averse to cycloheximide. [provided by MGI curators]
  • synonyms:
  • mt2r5,
  • mGR05,
  • T2R05,
  • Tas2r5,
  • T2r5,
  • Tas2r105,
  • taste receptor, type 2, member 105,
  • T2R9

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3 Driver For