Primary Identifier | MGI:1915005 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 67755 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and ATP-dependent activity, acting on DNA. Predicted to be involved in RNA splicing; extrinsic apoptotic signaling pathway via death domain receptors; and rRNA processing. Predicted to be located in nucleolus. Predicted to be active in nucleus. Is expressed in genitourinary system. Orthologous to human DDX47 (DEAD-box helicase 47). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. In vitro outgrowth assays show that blastocysts hatch from the zona pellucida but form irregular outgrowths. [provided by MGI curators] |