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Protein Coding Gene : Gucy2c guanylate cyclase 2c
Primary Identifier  MGI:106903 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  14917
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables guanylate cyclase activity. Acts upstream of or within regulation of cell population proliferation and response to toxic substance. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in plasma membrane. Is expressed in alimentary system; liver; and spinal cord. Used to study abdominal obesity-metabolic syndrome and obesity. Human ortholog(s) of this gene implicated in congenital diarrhea 6. Orthologous to human GUCY2C (guanylate cyclase 2C).
PHENOTYPE: Homozygous null mice are viable and have an increased resistance to heat-stable enterotoxins. [provided by MGI curators]
  • synonyms:
  • guanylate cyclase 2c,
  • MGD-MRK-35363,
  • Gucy2c,
  • GC-C,
  • MGI:2141513,
  • expressed sequence AI893437,
  • AI893437
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