Primary Identifier | MGI:1891823 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 60321 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein phosphatase regulator activity. Acts upstream of or within RNA splicing. Located in cytoplasm and nuclear speck. Is expressed in several structures, including blood; embryo ectoderm; embryo mesenchyme; extraembryonic component; and heart. Orthologous to human WBP11 (WW domain binding protein 11). PHENOTYPE: Mice homozygous for a null allele die prior to E8.5. Heterozygotes exhibit partial embryonic and postnatal lethality, and have defects in the axial skeleton, kidneys, and esophagus. [provided by MGI curators] |